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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SYT12 All Species: 39.09
Human Site: T339 Identified Species: 78.18
UniProt: Q8IV01 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IV01 NP_808878.1 421 46537 T339 R K M S K K K T A V K R D D P
Chimpanzee Pan troglodytes XP_001172576 455 50155 T373 R K M S K K K T A V K R D D P
Rhesus Macaque Macaca mulatta XP_001117977 421 46453 T339 R K M S K K K T A V K R D D P
Dog Lupus familis XP_540824 437 48192 T355 R K M S K K K T A V K R D D P
Cat Felis silvestris
Mouse Mus musculus Q920N7 421 46662 T339 R K M S K K K T A V K R D D P
Rat Rattus norvegicus P97610 421 46590 T339 R K M S K K K T A V K R D D P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P47191 424 47487 T331 K R L K K K K T T I K K N T L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001122205 420 46816 T338 R K I S K K K T S I K R D D T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P21521 474 53246 T381 K R L K K K K T S V K K C T L
Honey Bee Apis mellifera XP_001121685 991 110251 S907 K I H K K K T S V K K G E E S
Nematode Worm Caenorhab. elegans P34693 441 49885 T348 K R L K K K K T S I K K C T L
Sea Urchin Strong. purpuratus XP_784931 322 35947 K244 S K K K T S M K R S E T C P I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 92 97.3 91.7 N.A. 95 95.9 N.A. N.A. 23.5 N.A. 66.2 N.A. 24.8 21.2 22.6 34.4
Protein Similarity: 100 92.3 98.5 94 N.A. 97.3 97.8 N.A. N.A. 45.2 N.A. 81.4 N.A. 43.2 31.6 45.1 51.5
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. N.A. 33.3 N.A. 73.3 N.A. 40 20 33.3 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 73.3 N.A. 93.3 N.A. 73.3 46.6 73.3 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 50 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 25 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 59 59 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 9 0 9 9 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % G
% His: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 9 9 0 0 0 0 0 0 25 0 0 0 0 9 % I
% Lys: 34 67 9 42 92 92 84 9 0 9 92 25 0 0 0 % K
% Leu: 0 0 25 0 0 0 0 0 0 0 0 0 0 0 25 % L
% Met: 0 0 50 0 0 0 9 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 50 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 59 25 0 0 0 0 0 0 9 0 0 59 0 0 0 % R
% Ser: 9 0 0 59 0 9 0 9 25 9 0 0 0 0 9 % S
% Thr: 0 0 0 0 9 0 9 84 9 0 0 9 0 25 9 % T
% Val: 0 0 0 0 0 0 0 0 9 59 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _